Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

RNA-seq

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases.
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation.

Nature genetics·2026

Same author

Cohesin collisions maintain ordered nucleosome architecture at boundaries and promoters.

bioRxiv : the preprint server for biology·2026

Same author

ATF2 phosphorylation is a core transcriptional driver of neuron apoptosis.

Neuron·2026

Same author

Motif grammar and transcriptional programs decouple CTCF binding from nucleosome phasing to control cell-type-specific chromatin insulation.

Cell reports·2026

Same author

Chromatin architecture and physical constriction cooperate in phenotype switching and cancer cell dissemination.

bioRxiv : the preprint server for biology·2026

Same author

A Targetable Developmental Program Coregulates Angiogenesis and Immune Evasion in Melanoma.

Cancer discovery·2026

Same journal

Long-term molecular embedding of early life adversity: leukocyte DNA methylation and gene expression associations from childhood to young adulthood.

Epigenomics·2026

Same journal

Overview of transcriptomics and epigenomics approaches in the diagnosis, prognosis, and therapeutics of primary brain cancers.

Epigenomics·2026

Same journal

Ultra-sensitive urine DNA methylation test enables early and accurate detection of bladder cancer.

Epigenomics·2026

Same journal

Promoter methylation-associated brain-enriched long noncoding RNAs in glioblastoma: a multi-cohort public epigenomic re-analysis.

Epigenomics·2026

Same journal

Clinical diagnostic utility of <i>MGMT</i> promoter methylation.

Epigenomics·2026

Same journal

DNA methylation in glioblastoma: insights from single-cell epigenomics.

Epigenomics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 20, 2026

High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq

High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq

Published on: October 5, 2018

Interpreting 4C-Seq data: how far can we go?

Ramya Raviram¹, Pedro P Rocha, Richard Bonneau

¹Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.

|November 29, 2014

Summary

No abstract available in PubMed .

Keywords:

4C-Seq chromosomal interactions chromosome conformation capture resolution

More Related Videos

Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation

Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation

Published on: March 7, 2018

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

Published on: September 13, 2018

Related Experiment Videos

Last Updated: Apr 20, 2026

High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq

High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq

Published on: October 5, 2018

Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation

Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation

Published on: March 7, 2018

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

Published on: September 13, 2018