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Vaccines, emerging viruses, and how to avoid disaster.
1Novartis Vaccines, Siena 53100, Italy. rino.rappuoli@novartis.com.
BMC Biology
|November 30, 2014
Summary
Pioneering reverse vaccinology, Rino Rappuoli discusses pathogen genome screening for novel vaccine components. This approach holds potential for preventing future outbreaks like the current Ebolavirus epidemic.
Area of Science:
- Vaccinology
- Infectious Disease Research
- Genomic Medicine
Background:
- Rino Rappuoli's career spans significant contributions to vaccine development, including conjugate vaccines and acellular pertussis vaccines.
- His work at the Sclavo Research Center and Novartis Vaccines highlights a consistent focus on innovative vaccine technologies.
- Early research involved developing a diphtheria vaccine based on a non-toxic mutant toxin, a foundation for later conjugate vaccines.
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