Related Experiment Video
Updated: Apr 20, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
Shifting paradigm in the management of anal canal carcinoma
Supriya Mallick1, Rony Benson, P K Julka
1Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India, drsupriyamallick@gmail.com.
Background:
Anal canal is the lower most part of the gastrointestinal tract harbouring 4 % of all gastrointestinal cancer. Most common treatment for anal canal carcinoma includes chemoradiotherapy.
Methodology:
We reviewed the recent landmark trials to find a road map in the management of anal canal carcinoma.
Results:
Concurrent chemoradiotherapy appears to be the most effective treatment schedule. Induction, as well as maintenance chemotherapy, has no definite role. Moderate dose radiation 50.4-54 Gy with concurrent mitomycin C (MMC) and 5-fluorouracil (5-FU) remains the standard. Split course is detrimental. Intensity-modulated radiotherapy and targeted drugs are investigated.
Conclusion:
Combined modality therapy is the standard for anal canal carcinoma.
Related Concept Videos
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Urinary Tract Calculi VI: Surgical Management
