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Published on: July 31, 2016
Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma
Paras Karmacharya1, Naresh Bhandari2, Madan R Aryal3
1Department of Internal Medicine, Reading Health System, West Reading, PA, USA; paraskarmacharya@gmail.com.
Abstract:
Fulminant hepatic failure (FHF) is a relatively rare manifestation of Hodgkin's lymphoma. Clinical features, laboratory findings, and imaging of the liver are usually inconclusive, and liver biopsy may be required for confirmation. We present a case of an FHF in a woman 1 week after the diagnosis of Hodgkin's lymphoma. Chemotherapy could not be instituted due to hepatic encephalopathy and other complications. Autopsy revealed diffuse infiltration of the liver parenchyma. This case illustrates the importance of early diagnosis and institution of chemotherapy, which may reverse the liver failure.
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