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[Post-infectious autobullectomy].

J Vella-Boucaud1, S Chouabe2, F Bourin2

  • 1Service des maladies respiratoires, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France.

Revue Des Maladies Respiratoires
|December 1, 2014
PubMed
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A rare case of bullous emphysema showed spontaneous regression after infection, termed "autobullectomy". This finding suggests potential new therapeutic avenues for emphysema management.

Area of Science:

  • Pulmonology
  • Thoracic Surgery

Background:

  • Bullous emphysema involves airspaces larger than 10mm.
  • Spontaneous bulla regression (autobullectomy) is uncommon.

Observation:

  • A 37-year-old male smoker with prior pneumothorax surgery presented with emphysema and a right upper lobe bulla.
  • The patient developed community-acquired pneumonia with an air-fluid level within the bulla.
  • Antibiotic treatment led to decreased bulla size, confirmed by CT scan.

Findings:

  • Complete regression of a bulla was observed following a bacterial infection.
  • This event is described as a spontaneous "autobullectomy".

Implications:

  • Infection may trigger bulla regression through mechanisms like fibrosis or bronchial obstruction.
Keywords:
BulleEmphysemaEmphysèmeInfectionPulmonary bullaRégression spontanéeSpontaneous regression

Related Experiment Videos

  • This case highlights a potential, albeit unusual, natural resolution process for bullous emphysema.