Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

2.0K
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
2.0K
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

1.0K
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
1.0K
Stages of General Anesthesia01:22

Stages of General Anesthesia

2.5K
Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
2.5K
Skeletal Muscle Relaxants: Adverse Effects01:21

Skeletal Muscle Relaxants: Adverse Effects

1.1K
Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...
1.1K
Depolarizing Blockers: Pharmocokinetics01:19

Depolarizing Blockers: Pharmocokinetics

750
Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...
750
Skeletal Muscle Relaxants: Therapeutic Uses01:31

Skeletal Muscle Relaxants: Therapeutic Uses

1.2K
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of intrathecal morphine, lateral quadratus lumborum block, and their combination for analgesia and quality of recovery after Caesarean delivery: a randomised, double-blind, two-centre clinical trial.

British journal of anaesthesia·2026
Same author

Intra- and interrater reliability of quantitative ultrasound assessment of gastric content in patients with term pregnancy prior to elective Cesarean delivery.

Canadian journal of anaesthesia = Journal canadien d'anesthesie·2026
Same author

A Retrospective Cohort Assessment of Labor Epidural Catheter Replacement With Programmed Intermittent Epidural Bolus and Continuous Epidural Infusion.

Anesthesia and analgesia·2026
Same author

Why are clinical practice guidelines important in obstetric anaesthesia? Improving peripartum safety and quality of anaesthetic care through recommendations for labour pain.

Anaesthesia, critical care & pain medicine·2026
Same author

Clinician Perspectives on Obstetric Anesthesia Informed Consent for Patients With Limited English Proficiency: A Qualitative Study.

Women's health issues : official publication of the Jacobs Institute of Women's Health·2026
Same author

Neuraxial anesthesia in patients with placenta accreta spectrum disorder: balancing clinical strategy with shared decision-making.

Canadian journal of anaesthesia = Journal canadien d'anesthesie·2026

Related Experiment Video

Updated: Apr 20, 2026

Surgical Technique for Spinal Cord Delivery of Therapies: Demonstration of Procedure in Gottingen Minipigs
09:23

Surgical Technique for Spinal Cord Delivery of Therapies: Demonstration of Procedure in Gottingen Minipigs

Published on: December 7, 2012

15.9K

Persistent paralysis after spinal anesthesia for cesarean delivery.

Valerie Zaphiratos1, Dolores M McKeen1, Bruce Macaulay1

  • 1IWK Health Centre, Dalhousie University, Halifax, NS, Canada.

Journal of Clinical Anesthesia
|December 1, 2014
PubMed
Summary
This summary is machine-generated.

Anterior spinal artery syndrome, a rare complication of spinal anesthesia, caused permanent neurologic deficits in a cesarean delivery patient. This case highlights the importance of recognizing this serious neurologic event in obstetrics.

Keywords:
Adverse outcomeAnterior spinal artery syndromeCesarean deliveryNeuraxial anesthesiaNeurologic complicationParalysis/paraplegiaSpinal anesthesia

More Related Videos

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
04:33

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

Published on: November 8, 2024

1.1K
An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

22.2K

Related Experiment Videos

Last Updated: Apr 20, 2026

Surgical Technique for Spinal Cord Delivery of Therapies: Demonstration of Procedure in Gottingen Minipigs
09:23

Surgical Technique for Spinal Cord Delivery of Therapies: Demonstration of Procedure in Gottingen Minipigs

Published on: December 7, 2012

15.9K
Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
04:33

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

Published on: November 8, 2024

1.1K
An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

22.2K

Area of Science:

  • Neurology
  • Obstetrics
  • Anesthesiology

Background:

  • Neuraxial anesthesia is common in obstetric patients.
  • Anterior spinal artery syndrome is a rare but severe neurologic complication.
  • Permanent neurologic deficits following anesthesia require careful consideration.

Observation:

  • A healthy 32-year-old parturient developed anterior spinal artery syndrome after spinal anesthesia for cesarean delivery.
  • She experienced symptomatic bradycardia and hypotension post-anesthesia.
  • Persistent dense motor block and deficits consistent with anterior spinal cord lesion were noted.

Findings:

  • Magnetic resonance imaging showed no spinal cord compression or lesion.
  • Physical examination confirmed deficits affecting the anterior spinal cord at T6.
  • The syndrome occurred despite easily performed spinal anesthesia and clear cerebrospinal fluid.

Implications:

  • This case underscores the potential for anterior spinal artery syndrome after spinal anesthesia in obstetrics.
  • Early recognition and diagnosis are crucial for managing neurologic complications.
  • Further research may elucidate risk factors and preventative strategies.