Related Experiment Video
Updated: Apr 20, 2026

The Stroke Preclinical Assessment Network Multi-Laboratory Model of Thromboembolic Stroke with Thrombolysis: TE-MCAo
Published on: December 19, 2025
Population-based approaches for reducing stroke risk
Philip B Gorelick1, Muhammad U Farooq, Jiangyong Min
1Department Translational Science and Molecular Medicine, Mercy Health Hauenstein Neurosciences, MI State University College of Human Medicine, 220 Cherry Street SE Room H 3037, Grand Rapids, MI 49503, USA.
Abstract:
The global burden of stroke is particularly substantial in low- and middle-income countries. There are several risk factors or determinants of stroke and other cardiovascular diseases that are modifiable and have been shown to reduce the risk of stroke in at-risk persons. The high-risk or individual approach to prevention uses screening to identify such persons and medication is then usually required; however, to affect change in risk in a community, a population or mass approach is required to shift the community population to a lower risk profile. The community approach is usually accomplished through legislation, health education and wider economic means. In this review, the authors discuss the population approach to primary stroke prevention.
Related Concept Videos
Atherosclerosis III: Management
Atherosclerosis IV: Nursing Management
Ischemic Stroke l: Introduction
Coronary Artery Disease IV: Preventive Measures
Stroke: Introduction and Types
Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...

