Angioedema in the neurointerventional suite
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Updated: Apr 20, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Abraham Sonny1, Rafi Avitsian2, M Shazam Hussain3
1General Anesthesiology and Department of Outcomes Research, Cleveland Clinic, Cleveland, OH.
Abstract:
A 68-year-old woman with acute ischemic stroke presented for mechanical thrombectomy, after failed thrombolysis with intravenous recombinant tissue plasminogen activator. The procedure was completed successfully with dexmedetomidine infusion. However, she developed acute angioedema toward the end of the procedure requiring emergent fiberoptic-guided endotracheal intubation. Angioedema has been reported to occur after administering intravenous recombinant tissue plasminogen activator with an incidence of 1.3%-5.1% in patients with acute stroke.
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