Related Experiment Video
Updated: Apr 20, 2026

Primordial Germ Cell Transplantation for CRISPR/Cas9-based Leapfrogging in Xenopus
Published on: February 1, 2018
Genetic rescue to the rescue
Andrew R Whiteley1, Sarah W Fitzpatrick2, W Chris Funk3
1Department of Environmental Conservation, University of Massachusetts Amherst, Amherst, MA 01003, USA.
Abstract:
Genetic rescue can increase the fitness of small, imperiled populations via immigration. A suite of studies from the past decade highlights the value of genetic rescue in increasing population fitness. Nonetheless, genetic rescue has not been widely applied to conserve many of the threatened populations that it could benefit. In this review, we highlight recent studies of genetic rescue and place it in the larger context of theoretical and empirical developments in evolutionary and conservation biology. We also propose directions to help shape future research on genetic rescue. Genetic rescue is a tool that can stem biodiversity loss more than has been appreciated, provides population resilience, and will become increasingly useful if integrated with molecular advances in population genomics.
More Related Videos
05:48Removal of an Internal Translational Start Site from mRNA While Retaining Expression of the Full-Length Protein
Published on: March 16, 2022
10:07A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells
Published on: August 25, 2017
Related Concept Videos
What is Genetic Engineering?
Gene Conversion
Gene Conversion
In-vitro Mutagenesis
Homologous Recombination
CRISPR