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Updated: Apr 20, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
A case of periampullary adenocarcinoma in neurofibromatosis type 1
C Andrew Kistler1, Jennifer M Johnson1, Jordan M Winter1
11 Department of Medicine, 2 Department of Medical Oncology, 3 Department of Surgery, 4 Department of Pathology, 5 Department of Medicine, Division of Gastroenterology and Hepatology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Abstract:
Neurofibromatosis type 1 (NF-1) is an autosomal dominant genetic disorder with a known predisposition to gastrointestinal neoplasms such as stromal tumors and carcinoids. Adenocarcinomas (ACs) of the gastrointestinal tract are relatively rare in patients with NF-1, especially those found in the periampullary region. We present a case report of periampullary adenocarcinoma in a 56-year-old woman with NF-1 who presented with abdominal pain and obstructive jaundice.
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