Hypothyroid cardiomyopathy complicated by a left ventricular laminar thrombus

Area of Science:

• Cardiology
• Endocrinology
• Internal Medicine

Background:

• Clinical hypothyroidism is a common endocrine disorder affecting 0.3% of the U.S. population.
• Hypothyroidism impacts multiple bodily systems, notably the cardiovascular system through various mechanisms.
• Hypothyroid cardiomyopathy, a transient left ventricular systolic dysfunction, is an occasional complication.

Observation:

• A rare sequela of hypothyroid cardiomyopathy is the formation of a left ventricular thrombus.
• This phenomenon has been documented in only two previous case reports.
• We present a third case illustrating this rare complication.

Findings:

• The case involves reversible hypothyroid cardiomyopathy.
• A left ventricular laminar thrombus was identified as a complication of the cardiomyopathy.
• The findings highlight the potential for cardiac complications in hypothyroidism.

Implications:

• This case underscores the importance of recognizing and managing hypothyroidism to prevent cardiac complications.
• Early diagnosis and treatment of hypothyroidism may reverse cardiac dysfunction and thrombus formation.
• Further research into the mechanisms and management of hypothyroid cardiomyopathy and associated thrombi is warranted.