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Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
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Updated: Apr 20, 2026

VIGS-Mediated Forward Genetics Screening for Identification of Genes Involved in Nonhost Resistance
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Engineered plant virus resistance.

Leny C Galvez1, Joydeep Banerjee1, Hasan Pinar1

  • 1Department of Plant Pathology, University of Nebarska, Lincoln, NE 68583-0722, USA.

Plant Science : an International Journal of Experimental Plant Biology
|December 3, 2014
PubMed
Summary

Developing transgenic virus resistance in crops is crucial for durable, broad-spectrum protection against yield-reducing plant viruses. Genetic engineering offers a vital strategy to overcome limitations of traditional resistance methods.

Keywords:
AgrobacteriumBroad-spectrum resistanceGene silencingPlant biotechnologyPlant virusesTransgenic plants

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Area of Science:

  • Plant Pathology
  • Agricultural Biotechnology
  • Genetics

Background:

  • Virus diseases significantly limit crop production and cause substantial yield losses globally.
  • Current control methods like resistant cultivars and pesticides have limitations, including resistance breakdown and adverse environmental impacts.
  • Durable, broad-spectrum resistance strategies are essential for sustainable agriculture.

Purpose of the Study:

  • To review current strategies for developing virus-resistant transgenic plants.
  • To highlight the potential of genetic engineering in enhancing crop resilience to viral pathogens.
  • To discuss the advantages of transgenic approaches over conventional methods.

Main Methods:

  • Review of existing literature on plant gene transfer systems and genetic engineering for virus resistance.
  • Analysis of strategies for introducing alien genes into plant genomes.
  • Examination of various approaches for creating transgenic virus resistance in crops.

Main Results:

  • Genetic engineering provides diverse options for introducing transgenic virus resistance.
  • Transgenic plants offer a mechanism for broadening genetic resources for disease control.
  • Novel strategies can lead to durable and broad-spectrum resistance against viral pathogens.

Conclusions:

  • Transgenic technology is a promising approach to develop effective and sustainable virus resistance in crops.
  • Genetic engineering offers a powerful tool to overcome the limitations of conventional crop protection strategies.
  • Further development in this area is critical for ensuring global food security.