Effect of early enrollment on outcomes in cardiac rehabilitation

Dominic A Johnson1, Matthew T Sacrinty1, Pallavi S Gomadam1

  • 1Department of Internal Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina; Department of Cardiology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina.

Insights

Starting cardiac rehabilitation (CR) within 15 days of a cardiac event maximizes benefits for weight and exercise capacity. Delayed CR enrollment impacts patient outcomes, with significant improvements still observed but of lesser magnitude.

Area of Science:

  • Cardiology
  • Rehabilitation Medicine
  • Preventive Cardiology

Background:

  • Outpatient cardiac rehabilitation (CR) is recommended within 1-3 weeks post-cardiac event.
  • The impact of delayed CR enrollment on patient outcomes remains unclear.
  • Understanding factors influencing CR delays is crucial for optimizing patient recovery.

Purpose of the Study:

  • To investigate the effects of delayed enrollment in outpatient cardiac rehabilitation on patient outcomes.
  • To identify demographic and clinical factors associated with delayed CR initiation.
  • To determine the optimal timing for CR initiation to maximize patient benefits.

Main Methods:

  • A cohort of 1,241 patients undergoing CR after cardiac events or surgery was analyzed.
  • Risk factors and metabolic equivalent levels (METs) were assessed pre- and post-CR.
  • CR delay times were categorized (0-15, 16-30, >30 days) and correlated with outcomes.

Main Results:

  • Mean CR delay was 34 days; delays >30 days were linked to older age, female gender, nonwhite race, unemployment, and longer hospital stays.
  • Patients with delayed CR (>30 days) showed significant improvements but lesser gains in peak METs and weight compared to those starting CR earlier (0-15 days).
  • Multivariate analysis confirmed that delayed CR (>30 days) independently predicted reduced MET improvement (β = -0.59, p <0.001).

Conclusions:

  • CR enrollment timing varies significantly, influenced by patient demographics and initial hospital stay duration.
  • Delayed CR enrollment negatively impacts patient outcomes, particularly exercise capacity and weight management.
  • Initiating CR within 15 days of a cardiac event yields the greatest benefits for patient recovery and functional improvement.

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