Related Experiment Videos
[Clinical deterioration following chemonucleolysis. Sequestration or neurotoxic complication?]
P Wehling1, K P Schulitz, A Molsberger
1Orthopädische Klinik der Universität Düsseldorf.
Neurochirurgia
|May 1, 1989
Summary
Clinical deterioration after chemonucleolysis with chymopapain requires careful diagnosis. Differentiating sequestration from neurotoxic complications guides urgent surgical or cortisone treatment.
Area of Science:
- Neurosurgery
- Radiology
- Pharmacology
Background:
- Chemonucleolysis using chymopapain is a procedure for treating herniated discs.
- Complications can arise, necessitating accurate diagnosis and timely intervention.
Observation:
- A case report details a patient's clinical deterioration following chemonucleolysis.
- The study explores diagnostic and therapeutic strategies for post-procedure complications.
Findings:
- Distinguishing between sequestration and neurotoxic complications is crucial for effective treatment.
- Magnetic resonance tomography and spinal evoked nerve potentials aid in early differential diagnosis.
Implications:
- Immediate surgical intervention is required if a sequester forms.
- High-dose cortisone treatment is indicated for neurotoxic complications.