Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

6.8K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
6.8K
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

118
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
118
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

866
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
866
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

5.0K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
5.0K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

14.7K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.7K
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

611
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
611

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Factor XI and XIa Inhibitors for Venous Thromboembolism Prophylaxis After Total Knee Arthroplasty: A Review From Mechanism to Phase III Trials.

The Journal of arthroplasty·2026
Same author

Sports Unite All of Us.

The Journal of bone and joint surgery. American volume·2026
Same author

Advanced Practice Providers in Total Joint Arthroplasty: A National Assessment Demonstrates Increasing Prevalence and Unique Practice Characteristics.

The Journal of arthroplasty·2026
Same author

Adductor canal block catheters and post-TKA outcomes: Weighing pain management against complication risks.

Journal of orthopaedic surgery (Hong Kong)·2026
Same author

The One-Year Infection Rates After Vancomycin Powder and Dilute Povidone-Iodine Lavage in High-Risk Primary Total Joint Arthroplasty: A Multicenter Randomized Controlled Trial.

The Journal of arthroplasty·2026
Same author

The Persistent Challenges of Diagnosing Orthopaedic Implant-Related Infections.

The Journal of bone and joint surgery. American volume·2026

Related Experiment Video

Updated: Apr 20, 2026

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
04:37

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

1.4K

Prosthetic joint infections.

Antonia F Chen1, Snir Heller1, Javad Parvizi1

  • 1Department of Orthopaedic Surgery at the Sidney Kimmel School of Medicine, Rothman Institute, 925 Chestnut Street, Philadelphia, PA 19107, USA.

The Surgical Clinics of North America
|December 3, 2014
PubMed
Summary
This summary is machine-generated.

Prosthetic joint infections (PJIs) are challenging to treat. Exchange arthroplasty shows higher success rates than irrigation and debridement, particularly for resistant infections, but further research is needed for prevention.

Keywords:
DiagnosisIrrigation and debridementOne-stage exchange arthroplastyProsthetic joint infectionSuppressive antibioticsTwo-stage exchange arthroplasty

More Related Videos

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

11.7K
A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
06:18

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

Published on: March 3, 2023

2.0K

Related Experiment Videos

Last Updated: Apr 20, 2026

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
04:37

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

1.4K
Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

11.7K
A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
06:18

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

Published on: March 3, 2023

2.0K

Area of Science:

  • Orthopedic surgery
  • Infectious diseases
  • Biomedical engineering

Background:

  • Prosthetic joint infections (PJIs) pose significant challenges in orthopedic care.
  • Current management strategies include irrigation and debridement (I&D), staged arthroplasty, resection arthroplasty, fusion, or amputation.
  • Chronic antibiotic suppression is an option for non-surgical candidates.

Purpose of the Study:

  • To review current management strategies for prosthetic joint infections.
  • To compare the efficacy of different treatment modalities for PJIs.
  • To highlight the need for future research in PJI prevention.

Main Methods:

  • Review of existing literature on PJI management.
  • Comparison of success rates for I&D versus exchange arthroplasty.
  • Discussion of alternative treatments for complex or non-surgical cases.

Main Results:

  • Irrigation and debridement (I&D) demonstrates lower success rates compared to exchange arthroplasty for PJIs.
  • Exchange arthroplasty, especially 2-stage, offers better outcomes, particularly with resistant organisms.
  • Non-surgical options like chronic antibiotic suppression have limitations.

Conclusions:

  • Exchange arthroplasty is generally more successful than I&D for treating prosthetic joint infections.
  • Effective management of PJIs, especially those involving resistant organisms, remains a clinical challenge.
  • Further research is crucial to develop improved strategies for preventing prosthetic joint infections.