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Updated: Apr 20, 2026
Operating Procedures of the Electrochemotherapy for Treatment of Tumor in Dogs and Cats
Published on: October 24, 2016
New treatment modalities for brain tumors in dogs and cats
1Neurology and Neurosurgery, Department of Small Animal Clinical Sciences, VA-MD Regional College of Veterinary Medicine, Virginia Tech, 215 Duckpond Drive, Mail Code 0442, Blacksburg, VA 24061, USA.
Abstract:
Despite advancements in standard therapies, intracranial tumors remain a significant source of morbidity and mortality in veterinary and human medicine. Several newer approaches are gaining more widespread acceptance or are currently being prepared for translation from experimental to routine therapeutic use. Clinical trials in dogs with spontaneous brain tumors have contributed to the development and human translation of several novel therapeutic brain tumor approaches.
Insights
Newer treatments for intracranial tumors show promise in both veterinary and human medicine. Canine brain tumor trials are advancing novel therapeutic strategies for human translation.
Area of Science:
- Veterinary Medicine
- Neuro-oncology
- Comparative Oncology
Background:
- Intracranial tumors present significant mortality and morbidity in both human and veterinary patients.
- Standard therapies for brain tumors have limitations, driving the need for novel approaches.
Purpose of the Study:
- To highlight the role of canine brain tumor models in advancing novel therapeutic strategies.
- To discuss the translation of experimental therapies from veterinary to human medicine.
Main Methods:
- Review of current advancements in intracranial tumor treatment.
- Analysis of clinical trials involving dogs with spontaneous brain tumors.
- Examination of therapeutic approaches undergoing translation to human clinical use.
Main Results:
- Canine brain tumor models are instrumental in the development of new therapeutic strategies.
- Several novel approaches are progressing towards clinical application in human neuro-oncology.
- Clinical trials in dogs have facilitated the translation of innovative brain tumor treatments.
Conclusions:
- Comparative oncology, particularly using canine models, accelerates the development of effective brain tumor therapies.
- The translation of veterinary-developed brain tumor treatments offers significant potential for improving human patient outcomes.
