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Updated: Apr 20, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
[High-flow nasal cannula oxygen therapy in critical patients. Prospective study]
T R Velasco Sanz1, A B Sánchez de la Ventana1
1Departamento de Medicina Intensiva, Hospital Clínico San Carlos, , Madrid, España.
High-flow nasal cannula oxygen (HFNC) has a low incidence in intensive care, primarily used for moderate respiratory failure. While HFNC improves oxygen therapy for most patients, it doesn't always prevent intubation.
Area of Science:
- Critical Care Medicine
- Respiratory Therapy
- Pulmonology
Background:
- High-flow nasal cannula oxygen (HFNC) is an increasingly utilized respiratory support method.
- Its application in intensive care settings requires further analysis of incidence and outcomes.
Purpose of the Study:
- To determine the incidence of HFNC use in an intensive care unit.
- To evaluate the procedure's indications, complications, and effectiveness.
Main Methods:
- A prospective, descriptive study was conducted in intensive care units.
- Data collected included patient demographics, HFNC indications, complications, and therapeutic goals.
- Statistical analysis involved descriptive statistics using SPSS v18.0.
Main Results:
- The study included 12 patients, with an HFNC incidence of 0.95%.
- Primary indications were moderate respiratory failure (75%) and hypoxemia (58.3%).
- Complications were infrequent, including mouth-breathing and nasal injury; 91.7% showed improved oxygen therapy, and 50% avoided intubation.
Conclusions:
- HFNC use in intensive care is currently low.
- Moderate respiratory failure and high oxygen demand are key indications for HFNC.
- While effective in improving oxygenation, HFNC does not eliminate the need for intubation in all cases.
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