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First reported human case of native mitral infective endocarditis caused by Streptococcus canis
Myriam Amsallem1, Bernard Iung1, Claire Bouleti1
1Department of Cardiology, Bichat Claude Bernard Hospital, AP-HP, Paris Diderot University, Paris, France.
The Canadian Journal of Cardiology
|December 3, 2014
Summary
This study reports the first human case of native valve infective endocarditis caused by Streptococcus canis, a bacterium typically found in animals. The patient recovered after valve replacement and antibiotic treatment.
Area of Science:
- Infectious Diseases
- Cardiology
- Zoonotic Infections
Background:
- Infective endocarditis is a serious infection of the heart valves.
- Group G Streptococcus canis is a known zoonotic pathogen, but native valve endocarditis is rare in humans.
Purpose of the Study:
- To report the first human case of native valve infective endocarditis caused by Streptococcus canis.
- To highlight the potential for zoonotic transmission of S canis to cause severe human infections.
Main Methods:
- Case report of a 65-year-old woman with acute heart failure and sepsis.
- Diagnosis confirmed by blood cultures, echocardiography, and polymerase chain reaction (PCR) on the explanted valve.
- Treatment involved urgent bioprosthetic valve replacement and a tailored antibiotic regimen.
Main Results:
- The patient presented with severe mitral regurgitation and multiple embolisms.
- Blood cultures and valve PCR identified Streptococcus canis.
- Successful treatment with surgery and antibiotics led to recovery.
Conclusions:
- Streptococcus canis can cause severe native valve infective endocarditis in humans.
- Zoonotic transmission from animal contact should be considered in cases of unexplained endocarditis.
- Prompt diagnosis and surgical intervention are crucial for patient outcomes.
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