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Updated: Apr 20, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
[Juvenile nasopharyngeal angiofibroma with orbital extension]
A Hervás Ontiveros1, E España Gregori1, L Climent Vallano1
1Unidad docente de Oftalmología, Departamento de Cirugía, Universidad de Valencia, Hospital Universitario La Fe, Valencia, España.
Clinical Case:
The case is presented of a 21 year-old male with a history of left proptosis and diplopia of two weeks of onset. The MRI showed an ethmoid-orbital vascular lesion with anterior skull base invasion and orbital extension. Biopsy of the ethmoid confirmed fibrovascular tissue, which supported the diagnosis of angiofibroma.
Discussion:
It is a benign neoplasm with local characteristics of malignancy due to its ability to invade adjacent areas. In this case, the debut presented with manifestations of orbital extension. A broad and multidisciplinary approach is needed in order to improve prognosis.
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