Related Experiment Video
Updated: Apr 20, 2026

Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
Published on: March 11, 2016
Lenticonus diagnosis in Alport's syndrome: Anterior capsule apical angle calculation using Scheimpflug imagery
E Jarrín1, I Jarrín2, F Arnalich-Montiel3
1Servicio de Oftalmología, Hospital Rey Juan Carlos, Móstoles, Madrid, España.
Objective:
We describe a simplified method to detect anterior lenticonus. Three eyes of 2 patients with anterior lenticonus, plus 16 eyes from 16 healthy controls underwent Scheimpflug imaging of their anterior segment with Pentacam. The anterior capsule apex angle was manually identified and automatically measured by AutoCAD.
Results:
The mean angle was 173.06° (SD: 1.91) in healthy subjects, and 158.33° (SD: 3.05) in anterior lenticonus eyes. The angle obtained from patients was more than 3 SD steeper than those from healthy subjects.
Conclusions:
The apical angle calculation method seems to discriminate well between normal eyes and eyes suspected of having anterior lenticonus.

