Related Experiment Video
Updated: Apr 20, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
[Idiopathic intracranial hypertension in a patient with Chiari I malformation]
E Santos-Bueso1, J Porta-Etessam2, D Díaz-Valle1
1Unidad de Neurooftalmología, Servicio de Oftalmología, Hospital Clínico San Carlos, RETICS. Instituto de Salud Carlos III. Red Temática de Investigación Cooperativa. Patología ocular del envejecimiento, calidad visual y calidad de vida. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, España.
Case Report:
The case involves a 22-year-old woman who presented with headache and decreased vision. She showed asymmetric papilledema, and a 6-mm tonsillar descent was observed in the image tests. She was diagnosed with secondary intracranial hypertension coinciding with the symptoms of a Chiari malformation (MC).
Discussion:
Chiari malformation type I is the most common in this group of malformations, and is characterized by a greater than 5mm descent of the tonsils, being able to cause increased intracranial pressure and papilledema by blocking the flow of the cerebrospinal fluid. In this case, the MC was not the responsible for triggering the secondary intracranial hypertension, but a mere coincidence of both processes.
Related Concept Videos
Increased Intracranial Pressure l: Introduction
Increased Intracranial Pressure ll: Pathophysiology
Cerebral Edema ll: Pathophysiology
Cerebral Edema l: Introduction
Cytotoxic Edema: Pathophysiology
Glaucoma: Overview

