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Factors associated with asthma control in children: findings from a national Web-based survey
Mari Sasaki1, Koichi Yoshida, Yuichi Adachi
1Division of Allergy, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Insights
Low birthweight, obesity, and pet exposure before birth are linked to uncontrolled pediatric asthma. Severe rhinitis significantly increases the risk of poor asthma control in children.
Area of Science:
- Pediatric Pulmonology
- Environmental Health
- Allergy and Immunology
Background:
- Asthma control is the primary goal of treatment, yet its determinants remain incompletely understood.
- Identifying factors influencing pediatric asthma control is crucial for effective management strategies.
Purpose of the Study:
- To assess factors associated with asthma control in a general population of pediatric patients.
- To identify environmental, demographic, and comorbid disease associations with uncontrolled asthma.
Main Methods:
- A Web-based survey was conducted in June 2012 targeting Japanese children aged 6-11 years with current asthma.
- Asthma control was evaluated using the Childhood Asthma Control Test (C-ACT), with uncontrolled asthma defined as a C-ACT score <20.
- Associations between uncontrolled asthma and various factors were analyzed using multivariable analysis.
Main Results:
- Out of 3066 children with asthma, 14.6% had uncontrolled disease.
- Low birthweight (aOR 1.65), obesity (aOR 1.44), and pre-birth pet ownership (aOR 1.68) were associated with uncontrolled asthma.
- Comorbid allergic rhinitis, particularly severe rhinitis (aOR 3.88), was a significant risk factor, inversely correlated with C-ACT scores (p < 0.001).
Conclusions:
- A population-based survey identified several factors associated with poor pediatric asthma control.
- Factors like low birthweight, obesity, pre-birth pet exposure, and severe rhinitis are key indicators for identifying children at risk of uncontrolled asthma.
Background:
Although achieving and maintaining control of asthma is considered to be the goal of asthma treatment, determinants of asthma control are not fully understood. Our aim was to assess factors associated with asthma control among paediatric patients in the general population.
Methods:
In June 2012, a Web-based survey was conducted to identify Japanese children aged 6 to 11 yr who currently have asthma and evaluate control of their disease using the Childhood Asthma Control Test (C-ACT). Associations were evaluated among uncontrolled asthma (C-ACT score <20) between environmental factors, demographics and comorbid allergic diseases.
Results:
Among the 3066 children with current asthma, 447 (14.6%) had uncontrolled asthma. Multivariable analysis identified factors such as low birthweight (adjusted OR 1.65, 95% CI 1.25-2.18), obesity (adjusted OR 1.44, 95% CI 1.05-1.99) and pet ownership before birth (adjusted OR 1.68, 95% CI 1.24-2.29) to be associated with uncontrolled disease. Comorbid allergic diseases, especially rhinitis were a significant risk of uncontrolled asthma (adjusted OR for severe rhinitis: 3.88, 95% CI 2.50-6.00). The severity of rhinitis symptoms was inversely correlated with the C-ACT score (p < 0.001).
Conclusions:
A population-based Web survey showed an association between several factors and the control of paediatric asthma. The assessment of these factors may help identify the children at risk with uncontrolled asthma.
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