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Related Concept Videos

Feedback Inhibition00:46

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Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
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Related Experiment Video

Updated: Apr 20, 2026

Restraint to Induce Stress in Mice and Rats
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Reply to the editor

Tyler M Gunn1, James E Speicher2, Mark D Iannettoni3

  • 1Division of Cardiothoracic Surgery, University of Kentucky, Lexington, Ky.

The Journal of Thoracic and Cardiovascular Surgery
|December 3, 2014
PubMed
Summary

No abstract available in PubMed .

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