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Structure and expression of an integrated human papillomavirus type 16 genome amplified in a cervical carcinoma cell
H Shirasawa1, Y Tomita, A Fuse
1Department of Microbiology, School of Medicine, Chiba University, Japan.
The Journal of General Virology
|July 1, 1989
Abstract:
A cellular sequence containing the integrated human papillomavirus type 16 genome in a cervical carcinoma cell line QG-U was cloned and analysed. The transcriptionally active viral genome disrupted at the E2 and L2 open reading frames was amplified with its flanking sequences.