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The correlation between mid-brain serotonin transporter availability and intelligence quotient in healthy volunteers
Purpose:
This study was performed to investigate the association between the mid-brain serotonin transporter (SERT) availability and intelligence quotient (IQ).
Methods:
One hundred and thirteen healthy participants, including 52 male and 61 female subjects, were recruited. We used SPECT with [(123)I]ADAM images to determine the SERT availability in the mid-brain, and measured the subjects' IQ using the WAIS-R.
Results:
We found a significant positive correlation between the mid-brain SERT availability and the IQ of the participants. Even when controlling for age and sex, the significant association still existed.
Conclusion:
This result implied that the higher the SERT binding in the mid-brain, the better the IQ in healthy participants.
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