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Related Experiment Videos

[In utero fetal death].

T Quibel1, T Bultez1, J Nizard2

  • 1Service de gynécologie-obstétrique, CHI Poissy-Saint-Germain-en-Laye, 10, rue du Champ-Gaillard, 78300 Poissy, France.

Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
|December 3, 2014
PubMed
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This summary is machine-generated.

Intrauterine fetal death (IUFD) affects 2% of pregnancies globally. Key risk factors include maternal health, smoking, and fetal growth, with placental issues being a primary cause.

Area of Science:

  • Obstetrics and Gynecology
  • Perinatology
  • Fetal Medicine

Background:

  • Intrauterine fetal death (IUFD) presents a significant global health challenge, impacting approximately 2% of pregnancies worldwide.
  • Understanding the prevalence, risk factors, and causes of IUFD is crucial for improving perinatal outcomes.

Purpose of the Study:

  • To provide consistent data on IUFD prevalence.
  • To assess associated risk factors and causes.
  • To evaluate prevention strategies, diagnostic methods (fetal autopsy, MRI), and lactation inhibition management.

Main Methods:

  • Comprehensive literature search of French and English publications.
  • Utilized databases including PubMed and Cochrane Library.

Main Results:

Keywords:
Antepartum fetal deathAutopsie fœtaleClassification des morts fœtalesClassification of stillbirthFetal autopsyInhibition de la lactationIntrapartum fetal deathIntrauterine fetal deathLactation inhibitionMort antepartumMort fœtale in uteroMort intrapartumMort périnatalePerte de grossesseStillbirthfetal loss

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  • IUFD prevalence is 2% worldwide, 0.5% in France.
  • Major risk factors include maternal overweight, advanced maternal age, smoking, fetal growth restriction, placental abruption, hypertension, and diabetes.
  • Primary causes are placental anomalies, abnormal karyotypes, and congenital malformations.
  • Fetal autopsy remains the gold standard for examination; fetal post-mortem MRI is an alternative if autopsy is refused.
  • Lactation inhibition management involves cabergoline initiated within 24 hours postpartum if requested.

Conclusions:

  • Identified key maternal and fetal factors contributing to IUFD.
  • Highlighted the importance of fetal autopsy and MRI in diagnosis.
  • Provided guidance on lactation inhibition management.