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Updated: Apr 20, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
[Psychology and pregnancy loss]
G Legendre1, M Gicquel2, V Lejeune3
1Service de gynécologie-obstétrique, CHU d'Angers, 4, rue Larrey, 49033 Angers cedex 01, France; CESP-Inserm, U1018, équipe 7 : genre, santé sexuelle et reproductive, université Paris Sud, 94276 Le Kremlin-Bicêtre cedex, France.
Psychological factors like depression and anxiety are common after pregnancy loss but usually improve within a year. Empathetic care is crucial for a better patient experience.
Area of Science:
- Psychology
- Obstetrics
- Mental Health
Background:
- Pregnancy loss can lead to significant psychological distress.
- Understanding the interplay between psychological factors and pregnancy loss is vital for patient care.
Purpose of the Study:
- To evaluate the relationship between psychology and pregnancy loss.
- To review the psychological impact of miscarriage and stillbirth.
Main Methods:
- A comprehensive literature review was performed.
- Medline database was consulted for relevant studies up to April 2014.
Main Results:
- Psychological factors are significantly associated with recurrent miscarriage risk.
- Depression and anxiety are common post-loss, typically resolving within a year.
- Systematic psychological treatment did not show obvious benefits one year after miscarriage.
- Empathetic care from medical teams improves the psychological experience after pregnancy loss.
Conclusions:
- Psychological consequences of pregnancy loss are common and generally reversible.
- An empathetic approach is essential for supporting patients experiencing pregnancy loss.
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