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Intraventricular pleomorphic xanthoastrocytoma: a case report.
Ricardo Menendez1, Julio Fernandez, Alfredo Monti
1Hospital Bernardo Houssay, Division of Neurosurgery, Vicente Lopez, Argentina.
Turkish Neurosurgery
|December 3, 2014
Summary
This report details a rare case of pleomorphic xanthoastrocytoma (PXA), a brain tumor, found exclusively in the third ventricle. The successful surgical removal offers insights into managing this unusual glial neoplasm.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Pathology
Background:
- Pleomorphic xanthoastrocytoma (PXA) is a rare glial neoplasm, typically affecting younger individuals and comprising less than 1% of astrocytic tumors.
- Intraventricularly located PXA is exceptionally uncommon.
Observation:
- A 24-year-old male presented with symptoms including headaches, cognitive decline, and behavioral changes, indicative of increased intracranial pressure.
- Magnetic resonance imaging revealed a well-enhanced solid tumor situated entirely within the third ventricle.
Findings:
- The tumor was completely resected using a right fronto-pterional trans-lamina terminalis approach.
- Post-operative neuropathology confirmed the diagnosis of pleomorphic xanthoastrocytoma.
- No additional adjuvant therapy was deemed necessary.
Implications:
- This case represents the first documented instance of a solid PXA confined solely to the third ventricle.
- Highlights the importance of considering rare tumor locations and types in neurosurgical practice.
- Contributes to the understanding of PXA presentation and management in atypical locations.
