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Infective factors of male infertility among Nigerians

B O Ogunbanjo1, A O Osoba, J Ochei

  • 1Department of Medical Microbiology, University College Hospital, Ibadan, Nigeria.

Insights

Genital infections in Nigerian males are linked to infertility. Seminal fluid analysis revealed infective agents or pus cells in a significant percentage of infertile men, highlighting infection

Area of Science:

  • Reproductive Medicine
  • Andrology
  • Infectious Diseases

Background:

  • Male infertility is a significant global health concern.
  • Genital tract infections are implicated as a potential cause of male infertility.
  • Understanding the role of seminal fluid in infection transmission is crucial.

Purpose of the Study:

  • To investigate the prevalence of infective agents and abnormal seminal fluid indices in infertile Nigerian males.
  • To assess the association between genital infections and male infertility in the studied population.

Main Methods:

  • Seminal fluid analysis was performed on 782 Nigerian males presenting with infertility.
  • Examination included screening for various infective agents.
  • Assessment of seminal fluid indices such as sperm count, motility, and presence of pus cells.

Main Results:

  • Infective agents were identified in 7% (54) of the patients.
  • A significant number of pus cells, indicative of infection, was found in 25% of the remaining patients.
  • These infections were associated with abnormal seminal fluid parameters.

Conclusions:

  • Seminal fluid can serve as a medium for the spread of infective agents.
  • Sexually and non-sexually transmitted genital infections may contribute significantly to male infertility in Nigeria.
  • Targeting genital infections could be a key strategy in managing male infertility.

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