Related Experiment Video
Updated: Apr 20, 2026
08:21
A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis
Published on: October 26, 2020
5.8K
[Atherosclerotic renal artery stenosis]
Annales De Cardiologie Et D'Angeiologie
|December 3, 2014
Summary
Renal artery stenosis (RAS) management is evolving. Recent trials show medical therapy is effective for many, but intervention is crucial for high-risk patients with severe hypertension or declining kidney function.
Area of Science:
- Cardiology
- Nephrology
- Vascular Medicine
Context:
- Renal artery stenosis (RAS) presents diagnostic and management challenges.
- Fibromuscular dysplasia-related RAS is under-recognized in younger patients.
- Atherosclerotic RAS is linked to cardiovascular events and mortality.
Purpose:
- To review current management strategies for RAS in cardiologists.
- To evaluate recent randomized clinical trials (e.g., CORAL, ASTRAL).
- To discuss patient selection for intervention in RAS.
Summary:
- RAS can lead to ischemic nephropathy and hypertension.
- Medical management is effective for many RAS patients.
- Intervention is increasingly considered for high-risk presentations like flash pulmonary edema, declining renal function, and resistant hypertension.
Impact:
- Improved understanding of RAS pathophysiology and risk stratification.
- Guidance on optimal treatment pathways for diverse RAS patient populations.
- Potential for better patient outcomes through tailored therapeutic approaches.
Keywords:
Angioplastie des artères rénalesArterial hypertensionAtherosclerotic renal artery stenosisDysplasie fibromusculaire des artères rénalesHypertension artérielle résistanteInsuffisance rénaleSevere resistant hypertensionSténose athéromateuse des artères rénalesSystème rénine angiotensine aldostérone
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