[Simultaneous bilateral Wilms tumor]

Area of Science:

• Pediatric Oncology
• Nephrology

Background:

• Wilms' tumor, a common pediatric kidney cancer, rarely presents bilaterally.
• The prognosis for Wilms' tumor has significantly improved with advancements in treatment.

Observation:

• This report details two pediatric cases of synchronous bilateral Wilms' tumors.
• Bilaterality is an infrequent occurrence, affecting 4% to 8% of Wilms' tumor diagnoses.

Findings:

• Conservative surgical approaches combined with neoadjuvant chemotherapy and reduced radiation therapy demonstrate positive outcomes.
• The presented cases support the efficacy of current treatment trends for bilateral Wilms' tumor.

Implications:

• These findings reinforce the effectiveness of modern, less aggressive treatment strategies for rare bilateral Wilms' tumor cases.
• Optimized treatment protocols can lead to favorable prognoses even in uncommon presentations of pediatric kidney cancer.