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Infantile perineal protrusion in two monochorionic twins
Paola Cavicchioli1, Enrico Valerio2, Mario Cutrone1
1Department of Pediatrics, Ospedale Dell'Angelo, Mestre, Venice, Italy.
AJP Reports
|December 3, 2014
Summary
Infantile perineal protrusion (IPP) in identical twins suggests a genetic link. This rare condition resolved spontaneously in both infants within six weeks without lasting bowel issues.
Area of Science:
- Pediatrics
- Genetics
- Dermatology
Background:
- Infantile perineal protrusion (IPP) is a rare condition with approximately 100 reported cases.
- IPP is typically classified into congenital/familial, acquired (constipation-related), and lichen sclerosus et atrophicus-associated types.
Observation:
- This case report presents two female monochorionic-monoamniotic twins with infantile perineal protrusion (IPP) at birth.
- Both twins exhibited similar lesions that healed spontaneously within six weeks.
- Neither twin experienced any alvus disturbances during the follow-up period.
Findings:
- This is the first reported instance of IPP occurring in monochorionic-monoamniotic twins.
- The simultaneous occurrence of IPP in genetically identical twins supports the hypothesis of hereditary or genetic factors.
- The condition resolved spontaneously without intervention or long-term complications.
Implications:
- This case provides novel evidence for a potential genetic predisposition in the development of infantile perineal protrusion.
- Further research into the genetic underpinnings of IPP is warranted.
- Understanding the genetic basis may aid in early diagnosis and management of IPP.
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