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Updated: Apr 20, 2026

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
Published on: April 7, 2021
Approach to the patient with the acute respiratory distress syndrome
David R Janz1, Lorraine B Ware2
1Section of Pulmonary and Critical Care Medicine, Department of Medicine, LSU School of Medicine, 1901 Perdido Street, Suite 3205, New Orleans, LA 70112, USA.
Abstract:
Given the high incidence and mortality of acute respiratory distress syndrome (ARDS) in critically ill patients, every practitioner needs a bedside approach both for early identification of patients at risk for ARDS and for the appropriate evaluation of patients who meet the diagnostic criteria of ARDS. Recent advances such as the Lung Injury Prediction score, the Early Acute Lung Injury score, and validation of the SpO(2)/Fio(2) ratio for assessing the degree of hypoxemia are all practical tools to aid the practitioner in caring for patients at risk of ARDS.
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