[Benefits in reducing alcohol consumption: how nalmefene can help]
1Groupe hospitalier La Rochelle Ré Aunis, 208, rue Marius-Lacroix, 17000 La Rochelle, France.
L'Encephale
|December 3, 2014
Summary
Reducing alcohol consumption significantly lowers mortality risk for alcohol use disorder (AUD). New medications like nalmefene, combined with psychosocial support, offer effective treatment options for AUD patients seeking to decrease intake.
Area of Science:
- Public Health
- Neuroscience
- Psychiatry
Context:
- Alcohol consumption is a leading global cause of mortality and morbidity.
- Alcohol use disorder (AUD) affects millions, yet treatment rates remain low.
- Recent data challenges the fixed nature of AUD, supporting dimensional and remission-based perspectives.
Purpose:
- To highlight the public health imperative of increasing AUD treatment engagement.
- To explore the efficacy of reduced alcohol consumption as a treatment goal.
- To introduce novel pharmacotherapies and integrated treatment approaches for AUD.
Summary:
- Epidemiological data suggests AUD is not always a fixed entity, with significant remission rates observed.
- Reducing alcohol intake, even by moderate amounts, demonstrably lowers mortality risk.
- Nalmefene, an opioid receptor antagonist, shows promise in aiding reduced consumption when combined with the BRENDA psychosocial program.
Impact:
- Increased treatment participation and reduced alcohol-related mortality are achievable public health goals.
- Integrating reduced consumption into treatment guidelines by institutions like NICE and NIAAA reflects a paradigm shift.
- Pharmacological and psychosocial interventions offer a viable, well-tolerated pathway for patients to manage AUD and achieve personal reduction goals.
Keywords:
Alcohol use disorderBRENDAConsommation contrôléeControlled useNalmefeneNalméfènePharmacotherapyPharmacothérapiePsychotherapyTroubles liés à l’utilisation d’alcoolMore Related Videos
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