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Updated: Apr 20, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Unciflavones A-F, six novel flavonoids from Selaginella uncinata (Desv.) Spring
Hui Zou1, Kang-Ping Xu2, Fu-Shuang Li2
1School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China; Department of Pharmaceutical Science, Medical College of Hunan Normal University, Changsha, Hunan 410013, PR China.
Abstract:
Six new flavonoids, unciflavones A-F (1-6), have been isolated from medicinal plant Selaginella uncinata (Desv.) Spring. Their structures were established on the basis of extensive NMR analysis including 1D NMR ((1)H, (13)C and DEPT) and 2D NMR (COSY, HSQC, HMBC) experiments as well as HRESIMS analysis. All compounds possess exceptional structural features with an aryl substituent at the C-8 position, which are uncommonly encountered in natural resources and firstly reported in genus Selaginella.

