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Discovery of potent iminoheterocycle BACE1 inhibitors

John P Caldwell1, Robert D Mazzola1, James Durkin1

  • 1Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA.

Bioorganic & Medicinal Chemistry Letters
|December 3, 2014
PubMed

Keywords:
Alzheimer’s diseaseAspartyl protease inhibitorsBACEStructure-based drug designβ-Secretase

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