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Molecular basis for DPY-30 association to COMPASS-like and NURF complexes

Véronique Tremblay1, Pamela Zhang1, Chandra-Prakash Chaturvedi2

  • 1Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada.

Structure (London, England : 1993)
|December 3, 2014
PubMed
Summary

DPY-30 protein incorporation into COMPASS-like complexes is crucial for cell differentiation. Structural and functional studies reveal how ASH2L and DPY-30 interact, impacting histone methylation and erythroid development.

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