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Megaprosthesis in post-traumatic and periprosthetic large bone defects: Issues to consider
G M Calori1, M Colombo1, E Malagoli1
1C.O.R., Reparative Orthopaedic Surgery Department, Orthopaedic Institute G. Pini, University of Milan, Italy.
Injury
|December 3, 2014
Summary
Megaprosthesis implantation for severe bone loss offers a viable solution in complex non-oncological cases. Careful surgical technique and specialized centers are crucial for successful outcomes and long-term prosthesis survival.
Area of Science:
- Orthopaedic Surgery
- Biomaterials Engineering
- Reconstructive Surgery
Background:
- Megaprostheses, initially for oncological bone loss, are increasingly used for severe non-oncological bone loss.
- Indications include acute trauma, post-traumatic failures, and complex revision surgeries.
- These cases present unique challenges compared to oncological resections due to longer patient life expectancy.
Purpose of the Study:
- To retrospectively evaluate complications of lower limb megaprosthesis implantation in post-traumatic and prosthetic bone loss.
- To identify critical issues during and after surgery.
- To propose strategies for complication avoidance and management.
Main Methods:
- Retrospective analysis of complications in non-oncology patients.
- Inclusion of 72 patients treated with large resection mono- and bi-articular prostheses.
- Study period: January 2008 to January 2014.
Main Results:
- Key complications identified include limb length/rotation restoration, knee extensor mechanism reconstruction, and trochanteric reconstruction.
- Implant stability, dislocation, range of motion, skin coverage, sepsis, and bone quality were critical issues.
- Management of these factors is essential for successful megaprosthesis use.
Conclusions:
- Lower limb megaprostheses are a viable option for carefully selected non-oncological severe bone loss cases.
- Surgery requires specialized centers with advanced knowledge and technology.
- Rigorous surgical technique and implantation are necessary for long-term prosthesis survival in patients with longer life expectancies.

