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Updated: Apr 20, 2026
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Renal cell carcinoma subtype differentiation using single-phase corticomedullary contrast-enhanced CT
Filipe Veloso Gomes1, António P Matos2, João Palas2
1Department of Radiology, Hospital Garcia de Orta, Almada, Portugal; Department of Radiology, Hospital de Faro, Faro, Portugal.
Objective:
To compare multiphase and single-phase corticomedullary contrast-enhanced computed tomographic (CT) imaging in the differentiation of renal cell carcinoma (RCC) subtype.
Material And Methods:
Pathology records were reviewed from January 2008 to March 2013. The final cohort consisted of 79 patients (57 men, 22 women; mean age: 64±13). Quantitative tumor percentage enhancement (TE), cortical enhancement, and tumor-to-cortex enhancement (TCI) indexes were calculated.
Results:
Single-phase evaluations showed significantly lower mean TE and TCI for papillary tumors when compared with clear cell and cromophobe tumors (P<.01). Comparison of receiver operating characteristic curve analyses did not show significant differences between both evaluation methods.
Conclusion:
Accuracy of RCC subtype differentiation with single-phase corticomedullary contrast-enhanced CT is comparable to multiphasic imaging.
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