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Related Concept Videos

Narcolepsy01:07

Narcolepsy

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Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
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Sleep-Wake Cycles01:24

Sleep-Wake Cycles

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Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
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Sedatives and Hypnotics Drugs: Miscellaneous Agents

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Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
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CNS depressants include drugs from the category of barbiturates and benzodiazepines. They are valuable medications for managing anxiety disorders and insomnia. Barbiturates, once used to induce and maintain sleep, have been replaced mainly by benzodiazepines due to barbiturate's toxicity, tolerance, and overdose risks. They interact with GABAA receptors, leading to sedation at low doses and potentially coma and death at higher doses. Phenobarbital, a long-acting barbiturate, possesses...
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Management of Insomnia01:19

Management of Insomnia

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The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
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REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

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REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
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Narrating narcolepsy--centering a side effect.

Britta Lundgren1

  • 1a Department of Culture and Media Studies , Umeå University , Umeå , Sweden.

Medical Anthropology
|December 3, 2014
PubMed
Summary
This summary is machine-generated.

Parents navigated the aftermath of Pandemrix narcolepsy cases by creating shared narratives and personal coping strategies. This involved active meaning-making and knowledge work to manage the disease

Keywords:
A(H1N1)mass-vaccinationnarcolepsyparents’ narrativesside effects

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Area of Science:

  • Social Sciences
  • Public Health
  • Medical Sociology

Background:

  • The 2009-2010 A(H1N1) influenza pandemic in Sweden utilized Pandemrix mass vaccination, covering 60% of the population.
  • Post-vaccination, an increased incidence of narcolepsy was reported in over 200 children and young adults, linked to Pandemrix.

Purpose of the Study:

  • To explore parental experiences and meaning-making processes following Pandemrix-associated narcolepsy.
  • To analyze how parents construct narratives and knowledge to cope with the disease's aftermath.

Main Methods:

  • Qualitative analysis of interview data from parents of children diagnosed with narcolepsy.
  • Examination of narrative construction, knowledge work, and political engagement.

Main Results:

  • Parental experiences initiated collectively shaped critical public narratives and personalized learning journeys.
  • Parents engaged in active meaning-making, utilizing humor and cognitive strategies to manage the condition.
  • Bodies of children and parents became subjects and objects of knowledge, blending personal and political work.

Conclusions:

  • Parental responses to Pandemrix-related narcolepsy demonstrate significant meaning-making and knowledge-creation practices.
  • The study highlights the intersection of personal coping, collective narrative, and political action in managing vaccine side effects.
  • Reflective consciousness plays a crucial role in navigating the long-term consequences of adverse drug reactions.