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Related Experiment Video

Updated: Apr 20, 2026

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
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Does the IOFIX improve compression in ankle fusion?

Lee Parker1, Pinak Ray2, Stephan Grechenig3

  • 1SpR Trauma and Orthopaedic Surgery, The Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex HA74LP, United Kingdom.

Foot and Ankle Surgery : Official Journal of the European Society of Foot and Ankle Surgeons
|December 3, 2014
PubMed
Summary

The novel IOFIX device significantly enhances force distribution in ankle arthrodesis compared to traditional lag screws. This innovative intra-osseous fixation improves contact area, potentially leading to better surgical outcomes.

Keywords:
ArthrodesisCompressionFusionIOFIXLag screwX-post

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Area of Science:

  • Orthopedic Surgery
  • Biomechanical Engineering
  • Podiatric Medicine

Background:

  • The IOFIX is a novel intra-osseous fixation device designed to optimize force distribution during arthrodesis.
  • It features an "X-post" structure allowing a lag screw to enhance load sharing across the fused joint.
  • Previous biomechanical data on its efficacy was lacking.

Purpose of the Study:

  • To compare the force distribution and contact area of the IOFIX device against a conventional single lag screw in an ankle arthrodesis model.
  • To test the hypothesis that the IOFIX device offers no difference in force distribution compared to a single lag screw.

Main Methods:

  • A human cadaveric ankle model was utilized for the study.
  • Ten cadaver ankles were subjected to testing with both the IOFIX device and a standard single lag screw.
  • A pressure transducer was employed to measure and compare the forces generated by each fixation method.

Main Results:

  • The IOFIX device generated a significantly higher median average force (3.95kg) compared to the conventional lag screw (2.4kg) (p≤0.01).
  • The IOFIX also demonstrated a greater median average contact area (3.41cm²) across the arthrodesis compared to the lag screw group (2.42cm²) (p≤0.03).

Conclusions:

  • The IOFIX device significantly improves force distribution across an ankle arthrodesis.
  • These findings suggest the IOFIX offers a biomechanical advantage over single conventional lag screws for ankle fusion procedures.