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Pathogenic effect of osteopetrosis virus strain MAV-2(0) on guinea fowl pancreas
T T Kirev1, I A Toshkov, Z M Mladenov
1Institute of General and Comparative Pathology, Bulgarian Academy of Sciences, Sofia.
Abstract:
Osteopetrosis virus strain MAV-2(0) in guinea fowl pancreas induces early unspecific changes in separate acini and the development of neoplasia among apparently unaffected acinar tissue. The tumors were classified as serous and mucinous adenomas and adenocarcinomas, as well as poorly differentiated carcinomas. Foci of phenotypically altered acinar cells were observed in single experimental birds.
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