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Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
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Brainstem auditory evoked potentials in children with lead exposure.

Katia de Freitas Alvarenga1, Thais Catalani Morata2, Andrea Cintra Lopes1

  • 1Department of Speech Therapy and Audiology, Faculdade de Odontologia de Bauru, Universidade de São Paulo (FOB-USP), Bauru, SP, Brazil.

Brazilian Journal of Otorhinolaryngology
|December 3, 2014
PubMed
Summary

This study found no auditory effects from low chronic lead exposure in children. Comprehensive hearing tests revealed no association between blood lead levels and auditory function, suggesting safety at these low exposure levels.

Keywords:
Audiometria de tons purosBrainstem auditory evoked potentialsIntoxicação por chumboLead poisoningPotenciais evocados auditivos do tronco encefálicoPure-tone audiometryToxicidadeToxicity

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Area of Science:

  • Environmental Health
  • Pediatric Audiology
  • Toxicology

Background:

  • Previous research indicates lead exposure can affect children's hearing.
  • Further investigation into the impact of low-level, chronic lead exposure is necessary.

Purpose of the Study:

  • To assess the auditory system's response to low chronic lead exposure in children.
  • Utilized auditory electrophysiological tests to evaluate hearing function.

Main Methods:

  • A cross-sectional cohort study involving 130 children (18 months to 14 years).
  • Evaluated participants using tympanometry, audiometry, transient evoked otoacoustic emissions, and brainstem auditory evoked potentials.
  • Monitored blood lead levels over 35.5 months.

Main Results:

  • The average cumulative blood lead index was 12 microg/dL.
  • All children demonstrated normal hearing thresholds and transient evoked otoacoustic emissions.
  • No correlation was found between cumulative lead levels and auditory pathway nerve signal timing.

Conclusions:

  • Chronic low-level lead exposure did not show evidence of toxic effects on children's auditory function.
  • Findings suggest the auditory system in children is resilient to the low chronic lead exposures studied.