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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Correction: Prevention and management of cardiovascular disease in adults with cancer: an International Cardio-Oncology Society (IC-OS) and Multinational Association of Supportive Care in Cancer (MASCC) clinical practice statement.

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Assessment of Vascular Function in Patients With Chronic Kidney Disease
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Exercise training in CKD: efficacy, adherence, and safety.

Erin J Howden1, Jeff S Coombes2, Haakan Strand3

  • 1Schools of Human Movement Studies, University of Queensland, Queensland, Australia; Centre for Clinical Research Excellence-Cardiovascular Disease and Metabolic Disorders, University of Queensland, Queensland, Australia.

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|December 3, 2014
PubMed
Summary
This summary is machine-generated.

This study shows that a combined supervised and home-based exercise program significantly improves physical function in patients with chronic kidney disease (CKD). The exercise intervention was found to be effective, adhered to, and safe for this population.

Keywords:
Physical activityaerobic exercisecardiovascular riskchronic kidney disease (CKD)exercise capacityexercise traininglifestylemodifiable risk factormuscle strengthphysical functioningresistance training

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Area of Science:

  • Nephrology
  • Cardiology
  • Exercise Physiology

Background:

  • Cardiovascular disease (CVD) management increasingly incorporates exercise training.
  • Limited research exists on exercise training effectiveness in chronic kidney disease (CKD) patients, particularly in diverse populations.

Purpose of the Study:

  • To evaluate the effectiveness, adherence, and safety of a structured exercise program for patients with CKD stages 3-4 and uncontrolled cardiovascular risk factors.

Main Methods:

  • A randomized controlled trial analyzing secondary outcomes.
  • Participants received a lifestyle intervention including a 2-phased exercise program (8 weeks supervised, 10 months home-based) or usual care.
  • Efficacy was measured by metabolic equivalent tasks (METs), 6-minute walk distance, and body mass index; adherence by physical activity levels; and safety by serious adverse events.

Main Results:

  • 72 patients completed follow-up. The intervention group showed significant improvements in METs, 6-minute walk distance, and body mass index.
  • Self-reported physical activity increased at 6 months but decreased by 12 months in the intervention group.
  • No serious adverse events were reported in relation to the exercise training.

Conclusions:

  • The structured exercise program, combining supervised and home-based training, is effective for patients with CKD.
  • The program demonstrated good adherence and a favorable safety profile in the study population.
  • Further research is needed to fully assess the safety of exercise training regarding serious adverse events in CKD patients.