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Related Experiment Video

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Monitoring the Wall Mechanics During Stent Deployment in a Vessel

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Published on: May 8, 2012

Assessing bioresorbable coronary devices: methods and parameters.

Hector M Garcia-Garcia¹, Patrick W Serruys¹, Carlos M Campos²

¹Thoraxcenter, Erasmus, Rotterdam, the Netherlands.

JACC. Cardiovascular Imaging

|December 3, 2014

Summary

Bioresorbable vascular scaffolds (BRS) offer transient vessel support and drug delivery, avoiding long-term metallic stent issues. New assessment methods are needed to evaluate BRS safety and efficacy due to their unique design and degradation properties.

Keywords:

bioresorbable scaffolds coronary imaging intravascular ultrasound multislice computed tomography optical coherence tomography

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Last Updated: Apr 20, 2026

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Area of Science:

Biomaterials Science
Cardiovascular Engineering
Medical Imaging

Background:

Metallic drug-eluting stents (DES) have limitations, including long-term safety concerns.
Bioresorbable vascular scaffolds (BRS) offer transient support and drug delivery, aiming to overcome DES drawbacks.
BRS are designed to degrade completely, eliminating permanent vessel caging.

Purpose of the Study:

To review existing assessment methods for bioresorbable vascular scaffolds (BRS).
To highlight the need for novel imaging and methodologies for BRS evaluation.
To cover the spectrum of assessment techniques from noninvasive to invasive.

Main Methods:

Overview of noninvasive and invasive imaging modalities.
Discussion of light-based and sound-based assessment techniques.
Categorization of parameters into morphological and functional assessments.

Main Results:

Existing methods encompass a wide range of approaches for BRS assessment.
Evaluation requires consideration of BRS design, degradation rate, mechanical properties, and drug delivery.
A comprehensive understanding of these parameters is crucial for safety and efficacy.

Conclusions:

BRS technology presents a promising alternative to metallic DES.
New and adapted assessment methodologies are essential for BRS clinical translation.
Thorough evaluation ensures the safety and efficacy of bioresorbable vascular scaffolds.