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Updated: Apr 20, 2026

Flow Cytometry-Based Quantification and Analysis of Myocardial B-Cells
Published on: August 17, 2022
B-cell lymphoma of the heart: A rare diagnosis
António P Matos1, João Palas2, Constantinos Doulaptsis3
1Department of Radiology, Hospital Garcia de Orta, Almada, Portugal; Department of Radiology, UZ Leuven, Luven, Belgium.
Insights
We describe a rare case of primary cardiac lymphoma diagnosed in a 60-year-old woman. Multidetector computed tomography imaging was key to diagnosis, confirmed by histology and chemotherapy response.
Area of Science:
- Cardiology
- Oncology
- Radiology
Background:
- Primary cardiac lymphoma is a rare malignancy.
- Diagnosis can be challenging due to non-specific clinical presentations.
Observation:
- A 60-year-old woman presented with non-specific symptoms.
- Multidetector computed tomography revealed characteristic imaging findings suggestive of cardiac lymphoma.
Findings:
- Histopathological examination confirmed primary cardiac lymphoma.
- Tumor volume reduction after targeted chemotherapy validated the diagnosis.
Implications:
- This case highlights the importance of advanced imaging in diagnosing rare cardiac tumors.
- Understanding the imaging features of primary cardiac lymphoma aids in early detection and treatment planning.
Abstract:
We present a case of a primary cardiac lymphoma in a 60-year-old woman. The clinical presentation was non-specific and the diagnosis was suggested by its appearance on multidetector computed tomography. The final diagnosis was achieved by histopathological study and was corroborated by a decrease in tumor volume after targeted chemotherapy. A brief review of the appearance of primary cardiac lymphomas in imaging studies is presented.
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