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Insulin induces IRS2-dependent and GRK2-mediated β2AR internalization to attenuate βAR signaling in cardiomyocytes

Qin Fu1, Bing Xu2, Dippal Parikh2

  • 1Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Department of Pharmacology, University of California at Davis, CA 95616, United States.

Cellular Signalling
|December 3, 2014
PubMed

Keywords:
Adrenergic receptorCardiac contractilityGRK2Insulin receptorInternalizationcAMP

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