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Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
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Decrease in vitamin D status in the Greenlandic adult population from 1987-2010.

Nina O Nielsen1, Marit E Jørgensen2, Henrik Friis3

  • 1National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.

Plos One
|December 3, 2014
PubMed
Summary

Vitamin D status has significantly declined among Greenlandic Inuit from 1987 to 2005-2010, with young adults and those with lower traditional diet intake most affected. Increased dietary vitamin D and supplementation are recommended.

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Area of Science:

  • Arctic health research
  • Nutritional epidemiology
  • Vitamin D metabolism

Background:

  • Arctic populations face risks of low vitamin D due to limited sunlight and reduced traditional food consumption.
  • Investigating vitamin D status is crucial for public health in these regions.

Purpose of the Study:

  • To assess vitamin D status in adult Inuit in Greenland using serum 25(OH)D3.
  • To identify predictors of low vitamin D levels.
  • To examine trends in vitamin D status from 1987 to 2005-2010.

Main Methods:

  • Analysis of serum 25(OH)D3 in 2877 randomly selected adult Inuit.
  • Inclusion of a sub-sample (n=330) with blood samples from 1987 to assess temporal changes.
  • Statistical analysis to determine predictors and trends.

Main Results:

  • Serum 25(OH)D3 concentrations were lowest in 18-29 year olds (30.7 nmol/L) and increased with age.
  • A significant decrease in vitamin D status (32%-58%) was observed between 1987 and 2005-2010 across all age groups.
  • Low vitamin D (<50 nmol/L) affected 77% of young adults; predictors of higher levels included age, female gender, alcohol intake, and traditional diet; smoking, BMI, and latitude were associated with lower levels.

Conclusions:

  • A substantial decline in vitamin D status among Greenlandic Inuit has occurred.
  • Shifting away from traditional diets likely contributes to this decline.
  • Recommendations include increasing dietary vitamin D intake and considering supplementation.