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Published on: September 8, 2023
Endovascular treatment of multiple aneurysms complicating Cogan syndrome
Domenico Angiletta1, Paola Wiesel1, Raffaele Pulli1
1DETO Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Insights
Endovascular grafts effectively managed multiple aneurysms in Cogan syndrome (CS). This minimally invasive approach showed favorable long-term outcomes, offering a safe alternative for patients unsuitable for open surgery.
Area of Science:
- Vascular Surgery
- Cardiology
- Rheumatology
Background:
- Cogan syndrome (CS) can lead to complex aortic and carotid aneurysms.
- Managing multiple aneurysms in CS presents significant surgical challenges.
Purpose of the Study:
- To evaluate the efficacy of endovascular grafts in treating multiple aneurysms associated with Cogan syndrome.
- To assess the long-term outcomes of endovascular repair in a young patient with CS.
Main Methods:
- A 38-year-old female patient with descending thoracic aorta and right common carotid artery aneurysms due to CS underwent endovascular repair.
- Follow-up included angio CT scans and echo color Doppler assessments.
Main Results:
- Complete exclusion of aneurysms with no endoleak observed at 4-year follow-up.
- Carotid graft remained patent with no restenosis or disease progression in landing zones.
- Successful aneurysm exclusion was confirmed by imaging modalities.
Conclusions:
- Endovascular repair is a viable and effective treatment for multiple aneurysms in Cogan syndrome.
- This approach offers favorable long-term outcomes, especially for patients unfit for open surgery.
- Minimally invasive endovascular repair should be considered for complex aneurysms in young patients at high surgical risk.
Abstract:
To report the use of endografts to manage multiple aneurysms due to Cogan syndrome (CS). A 38-year-old woman with descending thoracic aorta and right common carotid artery aneurysms due to CS was treated with endovascular grafts. After 4 years, angio computed tomography scan demonstrated complete exclusion of the aneurysms with no signs of endoleak, whereas echo color Doppler showed patency of the carotid graft, no signs of restenosis, no progression of the disease in the landing zones, and complete aneurysm exclusion. Endovascular repair seems to have favorable long-term outcomes and should be considered a viable alternative to surgery in unfit for open surgery patients, even if they are young, and when the aneurysm size and location would pose a higher risk of perioperative and postoperative complications after an open surgical procedure.
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