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Laparoscopic Appendectomy Is Safe: Influence of Appendectomy Technique on Surgical-site Infections and
Maximilian Sohn1, Maria Hoffmann, Alfred Hochrein
1*Department of Abdominal, Vascular and Thoracic Surgery, Klinikum Bogenhausen, Städtisches Klinikum München GmbH GmbH ‡Department of General, Abdominal and Trauma Surgery, Chirurgische Klinik Dr. Rinecker, Munich †Department of General, Vascular and Thoracic Surgery, Charité - University Medical Center Berlin, Campus Benjamin Franklin, Berlin, Germany.
Purpose:
Surgical-site infections (SSIs) and intra-abdominal abscesses (IAAs) are the most frequent complications of appendectomy. The role of laparoscopy in the treatment of appendicitis remains controversial concerning the complication rate. The aim of this retrospective cohort study was to compare open and laparoscopic appendectomy for SSI and IAA.
Methods:
All patients undergoing appendectomy between January 1, 2007 and May 31, 2010 were included in the study. Perioperative data and data on postoperative complications were collected from patient files. A questionnaire was used to assess complications after discharge. Main outcome parameters were SSI and IAA. Open appendectomy (OAG) and laparoscopic appendectomy (LAG) were compared with univariate and multivariate analyses for the outcome parameters.
Results:
Four hundred thirty patients were included in the study. SSI (all: 10.6%, OAG: 11.7%, LAG: 7.5%, P=0.293) and IAA (all: 2.8%, OAG: 2.4%, LAG: 3.8%, P=0.506) were not significantly different between OAG and LAG. Risk factors for SSI were age (P=0.003), body mass index (P=0.017), ASA score (P=0.001), the intraoperative grade of inflammation (P=0.004), and the histologic grade of inflammation (P=0.015). The only risk factor for IAA was the intraoperative grade of inflammation (P=0.028). ASA score (odds ratio: 1.992, P=0.032) and the intraoperative grade of inflammation (odds ratio: 1.573, P=0.006) remained significant in the multivariate analysis for SSI.
Conclusions:
A higher ASA score correlates with SSI. A higher grade of intraoperative inflammation correlates with SSI and IAA. Laparoscopy has no impact on SSI and IAA in appendectomy.
Insights
This study found no significant difference in surgical-site infections or intra-abdominal abscesses between open and laparoscopic appendectomy. Higher ASA scores and intraoperative inflammation increase infection risk.
Area of Science:
- Surgical outcomes
- Infectious disease epidemiology
Background:
- Surgical-site infections (SSIs) and intra-abdominal abscesses (IAAs) are common after appendectomy.
- The comparative efficacy of laparoscopic versus open appendectomy for these complications is debated.
Purpose of the Study:
- To compare the rates of SSIs and IAAs between open appendectomy (OAG) and laparoscopic appendectomy (LAG).
- To identify risk factors associated with SSIs and IAAs following appendectomy.
Main Methods:
- Retrospective cohort study of 430 patients undergoing appendectomy from 2007-2010.
- Data collected via patient files and post-discharge questionnaires.
- Univariate and multivariate analyses compared OAG and LAG for SSI and IAA rates.
Main Results:
- No significant difference in SSI (11.7% OAG vs. 7.5% LAG) or IAA (2.4% OAG vs. 3.8% LAG) rates between OAG and LAG.
- Risk factors for SSI included age, BMI, ASA score, and inflammation grade.
- Intraoperative inflammation grade was the sole predictor for IAA.
Conclusions:
- Higher ASA scores and intraoperative inflammation are linked to increased SSI risk.
- Intraoperative inflammation also correlates with IAA development.
- Laparoscopic appendectomy does not significantly impact SSI or IAA rates compared to open appendectomy.
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